Synthetic virus-mimicking nanostructures for combinatorial immunotherapy
Intracellular delivery to immune cell subpopulations
Spatiotemporally controlled delivery via light sensitive nanomaterials
Modular scaffolds for vaccine delivery
About the Scott Lab
The Scott Lab develops immunoengineering tools that can collectively enhance our understanding of the immunological mechanisms behind vaccination and achieve rationally designed immunomodulation. We focus our efforts on professional antigen presenting cells (APCs), which are an essential link between innate and adaptive immunity, and investigate the means by which APCs receive information from and respond to their environment. We intend to accomplish this by engineering materials and optimizing protocols to examine or modulate key stages of APC activation and function: antigen scavenging, maturation and migration, and intercellular protein transfers.