Evan A. Scott Research Group

The Scott Lab develops immunoengineering tools that can collectively enhance our understanding of the immunological mechanisms behind vaccination and achieve rationally designed immunomodulation. We focus our efforts on professional antigen presenting cells (APCs), which are an essential link between innate and adaptive immunity, and investigate the means by which APCs receive information from and respond to their environment.  We intend to accomplish this by engineering materials and optimizing protocols to examine or modulate key stages of APC activation and function: antigen scavenging, maturation and migration, and intercellular protein transfers.