Northwestern University Robert R. McCormick School of Engineering and Applied Science

Evan A. Scott Research Group

Synthetic virus-mimicking nanostructures for combinatorial immunotherapyIntracellular delivery to immune cell subpopulationsSpatiotemporally controlled delivery via light sensitive nanomaterialsModular scaffolds for vaccine delivery

Synthetic virus-mimicking nanostructures for combinatorial immunotherapy

Intracellular delivery to immune cell subpopulations

Spatiotemporally controlled delivery via light sensitive nanomaterials

Modular scaffolds for vaccine delivery

About the Scott Lab

The Scott Lab develops immunoengineering tools that can collectively enhance our understanding of the immunological mechanisms behind vaccination and achieve rationally designed immunomodulation. We focus our efforts on professional antigen presenting cells (APCs), which are an essential link between innate and adaptive immunity, and investigate the means by which APCs receive information from and respond to their environment.  We intend to accomplish this by engineering materials and optimizing protocols to examine or modulate key stages of APC activation and function: antigen scavenging, maturation and migration, and intercellular protein transfers.